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Diazepam and alaprazolam both fall in the category of drugs that are known as Benzodiazepine drugs. Basically these are medications that are regarded as the sedative hypotonics, which are generally prescribed to those patients who are suffering from anxiety on short term basis. These drugs are also used in following conditions

  • pre-operative sedation,
  • management of alcohol withdrawal,
  • treatment of some seizure disorders

Also, they work as muscle relaxants. It is worth mentioning that doctors share the combined opinion that these drugs should not be prescribed for long term use as the patients can develop addiction of them, which not at all is a good sign.

In this section we will try to present a comparison of both of diazepam and alprazolam so that readers can get a better idea of them. Now the main factor that differentiates both these drugs is the associated half live. This means that how long a certain drug is capable of retaining its action in human body. The researches that have been carried upon both products showed that in comparison diazepam possesses a longer half life from this it can be evaluated that the effects that are introduced by this product inside human body stay active for extended periods of time. On the other hand the impacts produced by alprazolam live for shorter time periods. The experts normally regard Diazepam as long acting and alprazolam as an intermediate acting drug.

Mechanism of action

Both these drugs possess a common mechanism of action and work by influencing the central nervous system. They target the GABA receptors that are located in brain and this result in the initiation of an anxiolytic effect. Coming towards the dose that is associated with these drugs it is important to mention that its administration varies from patient to patient and doctors prescribe them after carefully evaluating the medical condition of the patient.

When consumed both of these drugs are metabolized inside human body by the action of enzymes that are present in liver. Because of this reason, there as an increase risk present that these drugs will interact with other medicines that are being consumed by the patient more specifically those medications which are that broken down by the liver. For this reason, it is advised that if you are taking any other medicine, then before starting anyone of the twoabove-mentioned drugs you must discuss the situation with your doctor and start taking them only if your physician gives you a green signal.

Availability

In most parts of this world there are very strict rules that deal with the distribution of Benzodiazepines and they are only given when prescribed by an able doctor. This restriction has been imposed because of the fact that these drugs possess an additive nature. Diazepam can be taken orally or can also be injected inside human body while Alprazolam can only be taken orally. Because of this diazepam can be used during acute conditions like in the management of Status epilepticus.

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